Episode 258 — Don’t Just Improve - RENEW
Guest: Dr. Nikesh Jasani & Dr. Nimesh Patel • Date: June 3, 2025
Episode Overview
My guests are Dr. Nikesh Jasani, an oncologist, and Dr. Nimesh Patel, an internal medicine physician, both of whom stepped beyond conventional protocols to pursue something more powerful: Renewal Therapy.
About Dr. Nikesh Jasani & Dr. Nimesh Patel
Dr. Nikesh Jasani is a board-certified oncologist and Medical Director of Educational Development at WBRx, with over 15 years of experience delivering compassionate, patient-focused care.
Dr. Nimesh Patel is a board-certified internal medicine physician and Chief Medical Officer at WBRx, known for integrating research-driven insights with hands-on patient care. Both doctors are advancing the use of Renewal Therapy to improve outcomes for patients with chronic conditions.
Learn more:
You’ll Discover
Why Modern Medicine Falls Short On Chronic Illness (3:04)
The Shocking Rise In Inflammatory Disorders (7:32)
How Renewal Therapy Helps The Brain And Immune System (12:17)
Why The Renewal Therapy Process Works Best When Paired With Core Foundations (15:22)
Full Transcript
Dr. Nikesh Jasani [00:00:00]:
Autism spectrum disorder has a lot of overlap with the benefits and the properties of stem cells because it is rooted in neural inflammation, immune dysregulation and glial imbalance in the brain. Blood brain barrier problems and synaptic issues that occurred at a very young age. And synapses are the connections between our neurons and they're miswired. Well, stem cells are a living drug. They know if they can get to that microenvironment, they can repair blood brain barriers. They can actually balance the microglial dysfunction of the immune system in the brain. This is what they do.
Len Arcuri [00:00:37]:
If you're a parent of a child with autism, you are being called to rise with love, courage and clarity. This journey isn't easy and most parents aren't equipped, but you can be. This podcast is your invitation to rise higher be because how you navigate matters. I'm Len and this is Autism Parenting Secrets, where you become the parent your child needs now.
Len Arcuri [00:01:02]:
Hello and welcome to Autism Parenting Secrets. It's Len and I am coming to you from the Autism Health Summit in San Diego, California. And here there's some really incredible presentations that are being made and my guests today have just delivered one of them and they were kind of mobbed afterwards. So this is in the area of therapy and approach that you can consider for your child. It's under the caption that you would probably know as stem cells. And again, I'm excited for my guests to be able to share with you their approach, how it might fit into what you're doing for your child. And with me is Dr. Nikesh Jasani and Dr.
Len Arcuri [00:01:39]:
Nimesh Patel. So they are here and I'm going to just stop talking and hand it off to them because they're pros, they can help explain this much better than I. And again, this is an emerging field. There's a lot of different options here and they're going to go deeper in terms of why. This is one that you definitely might want to consider. So welcome, gents. Thank you.
Dr. Nimesh Patel [00:01:59]:
And I can get started. A little background about myself. I'm a practicing internal medicine physician going on my 20th year. And through the scope of my practice, I realized I was improving quantity of life, but I didn't see the quality of life improvement. A lot of my patients, I was seeing more and more autoimmune disorders, more neurodegenerative disorders, more anti inflammatory disorders, and this chronic disease epidemic has gotten out of control and it's gotten worse. So I took a due diligence, kind of took a step Back in my practice, started focusing on what is the core cause. And when you get to the cellular level, you understand inflammation is the core root cause. That leads to a lot of these neurodegenerative disorders, along with mitochondrial dysfunction and oxidative stress, both exogenous and endogenous, that's occurring on a regular basis.
Dr. Nimesh Patel [00:02:52]:
Started approaching patients and discussing preventative therapies, focusing on clean nutrition and a anti inflammatory based diet, exercise and resistant training, reduction of stress and improvement in sleep hygiene. Well, even doing that, we still continue to see the progression of chronic disease and regression and aging progress. And that's where I took a step back and said, hey, what alternative therapies are out there that I can provide as a adjunct or a wellness product that would benefit the patient? And started understanding and looked into exosome therapy, peptide therapy, prp, cold plunge, infrared lights, everything you can think of. But one thing kind of zoned in all of those actually help on that core problem of inflammation. But one stood out, and that was mesenchymal stem cells. And understanding what these cells do that they have an innate behavior naturally to help in the healing process. They do three major things. They work on inflammation and reducing inflammation, they're immunomodulatory, and they basically help in regeneration.
Dr. Nimesh Patel [00:04:03]:
So we're born with these cells naturally and we have 1 in 10,000 that are stem cells when we're born. But as we age, it turns into 1 in 2 million. That's why we lose the ability to heal and our progression of healing faster is delayed as we get older. So ended up taking a journey, went down to Panama to get a better understanding of, you know, what's going on. Why are athletes going down there? Why are actors going down there? Why are kids with autistic disorders going down there? And we saw miraculous response. We would get testimonies from these individuals that saw improved cognitive function as well as motor function and came back and said, how can we implement this here in the States and how can it be utilized? Because the FDA is a very regulated process. And trying to go through the due diligence of going through phase four studies and spending billions of dollars in 15 years was not our approach. It was, hey, this is more of a wellness product.
Dr. Nimesh Patel [00:05:03]:
And this is not meant for a true treatment. It's really just an adjunctive treatment to help with what they were already taking from a pharmaceutical base. So ended up teaming up and partnering up with the reputable lab. And we, myself and Dr. Josani actually had to vet it because we as physicians were Taught one thing, do no harm. Sure. It's the first thing we're taught and we have to vet it from a standpoint of efficacy and quality basis because that is something we're going to recommend to our patients. So went through the due diligence and understanding how they procured the cells, what was the viability of the cells, what FDA registry they were part of, what testing they went through and completely were amazed on the due process.
Dr. Nimesh Patel [00:05:43]:
They had a ISO 5 room, which is a clean room within a clean room. And their processes were impeccable that we actually started renewal therapy and started utilizing the therapies on every disorder you can think of, from autism to Parkinson's and have seen miraculous responses. So I'll hand it over to my colleague, Dr. Josani. He'll give you a little more about the pathophysiology of how these cells work in our body.
Len Arcuri [00:06:12]:
And before we do, just a quick question, just out of curiosity. When you went down to Panama, did you go down with like a healthy skepticism, like wondering, hey, this doesn't. This seems almost too good to be true because I think a lot of our listeners probably are in that place now.
Dr. Nimesh Patel [00:06:25]:
Absolutely. Physicians are probably the most skep when it comes to anything and trying to understand, hey, is this something, you know, that really is going to help or not? And was fully skeptical and was still skeptical when I came back. And that's why I think it took us eight months to actually understand and really come to the understanding that hey, this is really working. It's working on the microenvironment in your body and it's actually helping the process of that regenerative issue and the healing that were lacking. And I was amazed by it.
Dr. Nikesh Jasani [00:06:58]:
There's a lot there to digest and it's spot on. You know, doctors are very skeptical. I come from a world where I'm treating cancer based on evidence based practices. These are patients that are very sick, but they're no different than me or you because I'm one step away from that myself. We all are. Cancer has no color, has nothing. It will affect everyone equally. And many of those patients I would see over the last 15 to 20, I'd say 18 years I've been practicing oncology.
Dr. Nikesh Jasani [00:07:26]:
I am seeing younger and younger patients coming in, not necessarily all with cancer, although some young cancers are definitely rising. It is increasing and then significant amounts of chronic disease. I mean obesity, insulin resistance, fatty liver, autoimmune conditions in younger and younger patients, people on eight to nine medications. And I'm looking back and Stepping back and looking at the forest from the trees to say what is happening? We are having more modern medicines than ever, yet people are sicker than ever. Well, we are in a evolutionary period where our metabolic health cannot match our environment. We have evolved over 50,000 years in a certain way where we are meant to move, be in the sun, we are meant to eat nutrient dense foods, we're meant to eat it in interval times. All of these things have changed in 40 years in a very short period. And we are now seeing lots of secondary diseases, in my opinion, from metabolic health derangements.
Dr. Nikesh Jasani [00:08:20]:
And if we wait till your disease and then we medicate to manage those symptoms, we don't get to the root cause. And yes, those medicines work and yes, we need them. Once you're diseased, our goal should be to step back 15, 20 years and make the alteration when people are younger, when you can alter their health in a meaningful way. And even people who are diseased, if I can manage their nutrition. The four pillars of health, always nutrition, exercise and detailed. I mean you have to guide people on low intensity zone 2, cardiovascular exercise, resistance training, nutrient dense protein based foods. You have to counsel people on sleep cycles and how they're very important to get some sunlight in the morning and evening and sleep correctly. How to have chronic stress management then if you need medicine and medical intervention.
Dr. Nikesh Jasani [00:09:04]:
Absolutely. And that's what led us to looking at renewal therapy. I myself had some autoimmune markers in my blood. Although I have no symptoms, I'm otherwise healthy. But I don't want to enter the medical system, I want to delay that. So I went and I did a lot of due diligence and I myself went to Panama and took the cells because I said, you know, there's enough data to tell me that there's a safety signal. And there's lots of trials being done in early conditions of autoimmunity, et cetera, to see if they alter the natural course. And lots of people, and I've met physicians down there, dentists, allied health science athletes.
Dr. Nikesh Jasani [00:09:39]:
I mean people were going down there all the time in their off seasons. But it's a very, well, high quality center. But not everyone is feasible to go over there. Those are MSCs. What we have figured out here, what renewal therapy is, it is a potent adjunct therapy. It is umbilical cord blood cell factor. That means cord live birds plan C sections. Same way, you take your cord blood and you harvest it and you can cryopreserve it, which I did for my kids.
Dr. Nikesh Jasani [00:10:09]:
It was offered and the same tissue bank took it and did it. I have access to it. The same ones take the donated cord to the lab that we work with closely and they process the cord blood, they remove the nucleated red cells and then they cryofreeze it. They check for 28 different pathogens and it is a very FDA compliant process the lab does. Most importantly, there's no manipulation of the shells. It is the stem cells that come in the cord blood, which is a wide variety, not just mesenchymal hematopoietic endothelial progenitor. There's very small embryonic cells. There are MSCs, mesenchymal and then other cytokines and growth factors.
Dr. Nikesh Jasani [00:10:48]:
And they're frozen, cryopreserved. But when you thaw them to give to someone, the cell viability is crucial for seeing if somebody has a response. That means the process of getting that cord blood to the time you freeze and thaw it is very, very important because there is a lot of cell damage that occurs to those cells. And when you thaw it, you figured out testing a lot of other products, the viability wasn't there. Those cells were like 5% viable, is that right? Yes. And it's not anyone's fault. We have to be honest about it. If it is, then that shouldn't be used until the process is correct to the point where you can try to get a high viability.
Dr. Nikesh Jasani [00:11:24]:
Many of them, good ones, are 40, 60% viable. We're upwards of 90% and we will tell you, third party tested, we have practices that use it and we will encourage them to. And this is why we see, I believe, the responses in all types of chronic inflammatory conditions. We can take it for neurodegenerative gastrointestinal inflammatory syndromes, autism spectrum disorder, osteoarthritis, and aging and health. I take it for aging. I've given this to my parents, I've given this to my in laws. They've had some dramatic responses from just arthritic conditions that nothing was fixing. And within weeks we noticed improvement.
Dr. Nikesh Jasani [00:12:02]:
Same thing with inflammatory bowel. Autism spectrum disorder has a lot of overlap with the benefits and the properties of stem cells because it is rooted in neural inflammation, immune dysregulation and glial imbalance in the brain. Blood brain barrier problems and synaptic issues that occurred at a very young age. And synapses are the connections between our neurons and they're miswired. Well, stem cells are a living drug. They know if they can get to that microenvironment, they can repair blood brain barriers. They can actually balance the microglial dysfunction of the immune system in the brain. This is what they do when they get to their environments.
Dr. Nikesh Jasani [00:12:40]:
They can release angiogenic factors, it can stimulate local regional stem cells. So this is all an orchestra. And then the downstream effects are, somebody's repetitive behavior may improve, their socialization may improve. It doesn't mean that the disease is cured. Same thing with a Parkinson's patient or an inflammatory bowel. We do not tell them the disease is cured. You stay with your medical specialist. But this is of the most potent complementary tools we've seen to really drive value.
Len Arcuri [00:13:08]:
So the disease isn't cured, but you've addressed the chronic inflammation.
Dr. Nikesh Jasani [00:13:12]:
And then you add on your nutrition should be there, your gut microbiome. And maybe you need your medicines with your doctor. But maybe you have had a real quality of life improvement that you were not seeing before.
Len Arcuri [00:13:22]:
But you can't skip the foundational.
Dr. Nimesh Patel [00:13:24]:
Correct. We would never turn that clock back where your biological age is going back. And that's the key. And then you have to stress those pillars that Dr. Giussani and I spoke about.
Len Arcuri [00:13:34]:
I got it. So when you work with families who are willing, who want to go down this road, they understand it. I'm guessing you advise them. Okay, well, first two steps, 1, 2, 3, and 4 from a foundation perspective, right?
Dr. Nikesh Jasani [00:13:47]:
We advise them.
Len Arcuri [00:13:48]:
In other words, this isn't like the quick fix that every parent's desperately wanting. If they do those foundational things first, they're set up much more.
Dr. Nikesh Jasani [00:13:56]:
We do tell them, but we do not. When they come to us or the practices that use these products, we just have to give very clear information that this isn't a cure all. This is an adjunct, a very potent adjunct of process. But we still want you to see your specialist, still do these other things that are very important because it's not a one size fits all in chronic disease. But this is a very potent tool that we've seen because there are people who've come in on their last leg and literally they were at their wit's end for all types of things, from neuropathic conditions to severe pain, from spinal issues, from autoimmune conditions. And we have seen dramatic responses in some of them. We cannot explain it always. And young people with inflammatory bowel will tell them, stay with your GI doctor.
Dr. Nikesh Jasani [00:14:41]:
You need to be on your biologics. And they're not improving. And some of them are, and some of them don't want to get on them. And we say, nope, still go to your doctor, you can try this, go with your diet, I mean, night and day. It's just like a 180 improvement. So we know it did something at the gut, inflammatory, at the level of the gut, but we know they still have the autoimmune condition. So you've got to attack it from all those other perspectives. And maybe you still need your medicines from your specialist, sit with them.
Dr. Nikesh Jasani [00:15:06]:
If your inflammatory markers go down, we tell them go back, their inflammatory markers drop. You can see the objective lab data improvement. So it's very interesting.
Len Arcuri [00:15:16]:
And so could you go a little bit more into what this looks like if somebody were to go down this road, what's the process? Because I know as I'm talking to you both and listening to what you're saying, I know with our son, we did not, my wife and I did not bank the umbilical cord blood. That was an option to us, kind of just declined, not thinking that we would need it. Now, in terms of the process that you have, like, you don't need something that you banked a long time ago. It's a much simpler process. So can you just describe high level, what that looks like?
Dr. Nimesh Patel [00:15:47]:
Yeah, I mean, if someone wants to get renewal therapy, it's just as easy as logging in online and getting a practice that's already utilizing the therapy. We obviously are throughout the whole US So it's not isolated to one city or one state, but we can actually drop ship the cord blood to wherever the location is and do the infusion. The infusion is a 5 to 10 minute procedure. It's intravenously and it's pretty quick and.
Dr. Nikesh Jasani [00:16:16]:
We haven't seen any reactions. There's been over 300,000 infusions from there over the years. We don't see reactions, there's no typing involved. So we tell people we don't feel there's a downside effect. The most is maybe you don't feel it. If you don't feel it, there is definitely some subclinical inflammation improved.
Len Arcuri [00:16:32]:
So even though it's not your own.
Dr. Nikesh Jasani [00:16:33]:
Stem cells, there is no typing. And in fact, the clinical trials in the US are using the same allogeneic umbilical cord cells in their tribe.
Len Arcuri [00:16:42]:
From a convenience standpoint, there's no requirement to travel to Panama or to go somewhere else.
Dr. Nikesh Jasani [00:16:47]:
It's feasible. At least it gives people some hope. And we don't want to give hype only. We have to be real and give very honestly what it does and what it may not do. And then we tell people wait, give yourself 90 days and just log, journal, see how the person is. We have seen all kinds of things. When people come back and we tell people, stay with your doctors, keep getting your testing.
Len Arcuri [00:17:08]:
Right, right, right.
Dr. Nikesh Jasani [00:17:09]:
Yeah.
Len Arcuri [00:17:09]:
Now the key is that this could be something to add on.
Dr. Nikesh Jasani [00:17:11]:
Exactly. We do not tell you to get off your med. That would be dangerous. We cannot honestly tell people that either.
Dr. Nimesh Patel [00:17:17]:
But in that same realm, as they see that improvement, they may be able to come off some of their meds based on that aspect. Because now you've turned that clock back, you've turned that biological aging back where they may not need as much polypharmacy as they were getting previously.
Dr. Nikesh Jasani [00:17:34]:
And many of them with improvement in autism and other chronic disorders. If they do double down then and do more, we more benefit. We see a lot more benefit, especially in the people that notice the initial benefits. When we take it for longevity and health, for us, it's very hard. We know it's doing something someday. Inflamed person with a lot of diseases. So they'll tell us within two, three weeks. Sometimes they're starting to see a difference.
Dr. Nikesh Jasani [00:17:56]:
Tell them, just wait.
Len Arcuri [00:17:58]:
Yeah. If you're doing it from an anti aging standpoint, you may not notice anything significant, but you also won't necessarily see the downside that could have happened if you didn't do it. So it's a little bit harder to identify. But I love this conversation. Again, in the spirit of helping parents particularly know what they're aiming for. And while nobody agrees on anything, and you can always focus on different root causes depending on what's going on with your child, the smart money is on if you're really addressing systemic chronic inflammation in the body in a number of ways. This is one, perhaps in addition, a very powerful way of accelerating everything else that you might be doing with your practitioner. And so in that standpoint, I think this is a very useful, powerful conversation to help informed parents.
Dr. Nikesh Jasani [00:18:44]:
Absolutely.
Len Arcuri [00:18:45]:
If they do want to know more about what you particularly do, how would they reach out and how would they get in contact with you?
Dr. Nikesh Jasani [00:18:51]:
They could even go simply to the website and start to read www.wbrxrenewalthherapy.com and you can start to read and then connect from there. And they're always being willing to connect you with one of the practices utilizing this near you.
Len Arcuri [00:19:06]:
Fantastic. Well, yeah, so overall, this whole conversation kind of can be summed up where don't just go for improvement, go for renewal. And this renewal therapy is a, is a super exciting one. So gentlemen, I really appreciate you spending time with me today. Thank you.
Dr. Nikesh Jasani [00:19:20]:
Thank you so much.
Len Arcuri [00:19:21]:
Your child needs you. Running on all cylinders now. And the fastest way to rise is with personalized one on one support. Get started today. Go to Eleanor. Elevate how you navigate dot com.
